Abstract: In this paper, the structures similar to those of different zonesin the Heat-Affected Zone (HAZ) of actural welding were obtained in the fatigue specimens with the thermal-simulated technique; the experiments on fatigue life and crack propagation were carried out with the specimens. Through the corrosion fatigue behavior of the different zones in HAZ investigated, the effect of welding process on the corrosion fatigue properties of CF-60 steel was studied. It was found that welding could reduce the corrosion fatigue properties of CF-60 steel because the fatigue properties of the Imcomplete Recrystal Zone (IRZ) in HAZ were worse than those of matrix and the other zones. One of the main reasons that resulted in the case was that the anti-corrosin of IRZ was worst in the welded joint region.