Abstract: Schedule rules for two-strand thin slab casting and rolling were established. Based on the characteristic of the casting and rolling process, a kind of coding, crossover operator, mutation operator and the concept of amendment operator for the genetic algorithm were proposed. In the genetic algorithm, the schedule rules were introduced into the modeling of initial population and the operation of amendment. A scheduling system of two-strand thin slab casting and rolling was developed by using the schedule rules and the genetic algorithm. This system can solve the dynamic schedule problem of two-strand thin slab casting and rolling and optimize production management.