层状仿生生物活性人工软骨植入体的数字散斑相关分析

Full-field deformation measurement of bionic artificial cartilage/bone composites using digital speckle correlation method

摘要: 制备了一种仿生层状人工软骨/骨复合植入体,可将软骨植入体与宿主软骨的连接转变为骨-骨的界面结合,提高植入软骨固定效果.采用数字散斑等方法对仿生层状人工关节软骨/骨复合植入体的生物力学性能进行研究,比较了松质骨,PVA/骨复合体以及PVA-BG复合体在不同载荷作用下的位移变化,并从微观变形角度探讨了人工软骨/骨复合植入体中软骨层厚度对缓冲内部应力的作用.

Abstract: The bionic bioactive artificial cartilage/bone composites implants were prepared by casting bioactive hydrogels onto the cancellous bone according to the structures of nature cartilage.This new kind of cartilage implants could improve the inferior connection of the implants with host cartilage by means of bone-bone interfacial interaction.The digital speckle correlation method was used to investigate the bio-mechanical properties of the artificial cartilage/bone composites.The micro-deformation of the cancellous bone,PVA/bonecomposites and PVA-BG/composite under different compressed loads were compared,which could show the cushion action of the artificial cartilage in the range of microscale.