Abstract: In order to gain ideal parameters of boreholes along coal seam for methane drainage, based on the gas flow theory in coal seam and the law of mass conservation, a mathematical model of the flow equation for draining methane through boreholes was established to study the methane flow field around drainage boreholes along coal seam. No. 5213 working face of Xinzhuangzi Coal Mine was taken as the field for simulating methane flow with MATLAB software. The simulation result was compared with actual drainage effect of the mine. Finally, the methane drainage parameters suitable to coal seam of the mine were obtained through analysis. The parameters can be applied and popularized in Huainan Mining Area with similar conditions of coal seam storage, which is beneficial to safety production for high methane mines.