Abstract: The construction overviews of nuclear power plants in recent years in China and the results of localization of seamless tubes for nuclear power were introduced. Aiming at the strategy of using the third generation nuclear power technology, which is represented by AP1000, to construct nuclear power plants, the technical requirements of seamless steel tubes for the third generation nuclear power plants were brought forward, and some issues related with quality control, product development and standard production were put forward to be concerned in the process of seamless tube localization for nuclear power.