Abstract: Geo-stress distribution in a mining area was analyzed by means of a partial least squares regression method (PLSRM). Based on data measured in Wushaoling tunnel ridge section, a numerical simulation of the initial geo-stress field around the area was performed using the commercial software ANSYS. Partial least squares regression analysis was carried out through actual measurement data and calculation results of geo-stress, and then fitting data was ready. Compared with the traditional least squares method, due to the advantage of principal component analysis in applying PLSRM, the present method decreases the regression error caused by the correlation between response variables. It can more effectively reflect the features of discontinuous geo-stress distribution and thus provides effective data support for establishing the geo-stress field.