Abstract: The effects of different inclusions on antimony precipitation and enrichment in steel during high-temperature oxidation were investigated. It is found that in the Fe-1.5%Sb alloy specimen, antimony-enriched phases precipitate at grain boundaries after water-quenching at 1100℃. Manganese sulfide is more favorable for antimony precipitation than oxide inclusions. The chemical composition of antimony-enriched phases is close to that of FeSb, which is consistent with the result calculated by the disregistry of lattice parameters between antimony particles and the inclusions. Reducing the oxygen content or adding Ti in steel can increase the amount of manganese sulfide and promote antimony precipitation, thereby decrease the amount of antimony segregation and solid solution, and change the precipitation location of Sb in steel.