Abstract: Because of the low cost, easy preparation, and good temperature stability, Fe-based amorphous alloys with excellent mechanical properties, magnetic properties, and corrosion resistance have been widely studied. Fe-based amorphous alloys can be used as anti-irradiation materials since their inherent disordered structure helps to resist the damage caused by irradiation. Thus, irradiation can be used to test the performance of these alloys and optimize their structure. The progress of research on the irradiation properties of Fe-based amorphous alloys is summarized in this article, which focuses on the study of neutrons, ions, and electron irradiation performance. The relationships between different amorphous alloy components and the type, energy, fluence of irradiated particles, structure, and properties of the alloys are discussed, and the crystallization mechanism induced by irradiation is evaluated. The results obtained can provide a valuable reference for promoting the development of Fe-based amorphous alloys.